Vitamin B12 is an important cofactor for energy metabolism. It works with folate in the methionine synthase pathway, which supports healthy homocysteine metabolism in the synthesis of S-adenosyl-methionine (SAMe), an important methyl donor. As such, it supports methylation for key biochemical reactions occurring in blood cells, neurons, the vasculature, and many other tissues. Through this pathway, Vitamin B12 is required for proper red blood cell formation, neurological function, and DNA synthesis. The activated and methylated form methylcobalamin is the primary form found in the cytosol of cells and predominates in blood and other fluids. This is the form of vitamin B12 primarily used for SAMe production, making it an important nutrient for healthy cell development, including red blood cells. At Pure Encapsulations, we're dedicated to providing nutritional supplements you can trust. That’s why our products are formulated using high quality, pure ingredients FREE FROM unnecessary additives and many common allergens, and backed by verifiable science. Everything you need and nothing you don't, that’s goodness encapsulated. When developing our products, we work in close collaboration with leading medical professionals and nutritional experts to create premium dietary supplements that you can feel good about. We source high-quality ingredients from the best suppliers, conduct research and clinical trials to confirm efficacy and safety, and undergo additional testing by accredited and cGMP-certified laboratories to ensure product purity and potency. We also believe in transparency, so every ingredient we put into our products, even if it’s just a trace amount, is listed on the label. If there’s an ingredient sourced from a possible allergen—we call that out too.