Traditional allergy supplements and anti histamine probiotic formulas can often only focus on reducing histamine within the gut by utilizing enzymes to degrade the histamine. nfortunately, this means they are limited in their function and only effective for reducing ingested histamine (i.e., histamine introduced to the body through the food we eat) within the GI tract. However, mast cells release histamine systemically. Therefore, when mast cells are activated, they release histamine throughout the body. Enzymes such as DAO do nothing to address the healthy function of mast cells or support the body's healthy response to histamine and therefore serve limited benefit. HistaQuel utilizes a comprehensive approach to support healthy mast cell function and histamine response systemically. Six clinically researched flavonoids and herbs have been combined to promote healthy levels of histamine production and healthy levels of histamine absorption. This holistic approach resulted in a comprehensive formula featuring dual mechanisms of action. The HistaQuel formula combines the benefits of many different natural immune support formulas, such as black seed oil capsules, stinging nettle capsules, black cumin seed oil capsules, a cumin supplement, or stinging nettle tincture. This is because this formula uses the core ingredients found in these standalone supplements, but combines them in a synergistic way that can help support both a healthy histamine response and mast cell function. So if you have been curious to see how black cumin oil, nettle leaf capsules, nettle leaves, or a black seed oil supplement can help support your immune system, consider giving this synergistic formula a try.*